Yes, depending on the case when we are talking about smart business apps then the KPIs and tile representation behind them could be configured.
Often times for instance some analytical apps in the starter system are delivered in the EUR currency and one of the first exercises we as a implementation team do is modify that to suit the customer landscape.
The central Fiori app to accomplish these exercises is 'Manage KPIs and Reports.' Below please find the relevant documentation. I believe there is also a section on creating/editing apps/tiles.
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